Background: Breast cancer is one of the causes of mortality in the world. Half of patients with metastatic extend resistance to Tamoxifen and almost all patients eventually become resistant to tamoxifen. Inorder to counteract with the negative effects of tamoxifen. this drug have been placed in combination with the curcumin. https://www.marketingjeunesse.com/product-category/curl-re-coiling-treatment/