Abstract Regulatory T cells play a crucial role in orchestrating immune response and maintaining immune tolerance. and the expression of the Foxp3 gene is indispensable to the differentiation of regulatory T cells. IL-4 shows strong inhibitory effects on Foxp3 expression and regulatory T cells differentiation. but the detailed mechanisms are still unclear. https://www.bekindtopets.com/quick-save-Nobivac-Feline-1-HCP-top-super/