Background & Aims: HBV-related acute-on-chronic liver failure (HBV-ACLF) is a severe acute liver injury secondary to HBV-related chronic liver disease (with or without cirrhosis) and is characterized by a high short-term mortality rate. Presently. there is a paucity of experimental models that specifically focus on HBV-ACLF based on chronic hepatitis B. Therefore. https://www.spidertattooz.com/Roikkuvat-varikkaat-perhos-korvakorut/